![]() The most important factors are the following: The prognosis for a given patient depends on several factors. Night sweats alone do not confer an adverse prognosis. The most significant B symptoms are fevers and weight loss. Unexplained fever with temperatures above 38☌.Unexplained weight loss (more than 10% of body weight in the 6 months before diagnosis).The B designation is given to patients with any of the following symptoms: PET-magnetic resonance imaging scans may be equivalent to PET-CT in obtaining staging information at 25% of the radiation dose.Īll stages of HL can be subclassified into A and B categories: B for those with defined general symptoms (described below) and A for those without B symptoms. Computed tomography (CT) of the neck, chest, abdomen, and pelvis or metabolic imaging (fluorine F 18-fludeoxyglucose positron emission tomography ) with PET-CT.Chemistry panel (electrolytes, blood urea nitrogen, creatinine, calcium, aspartate transaminase, alanine aminotransferase, bilirubin, and alkaline phosphatase) plus lactate dehydrogenase, uric acid, and phosphorus.Complete blood cell count and platelet count.History, with special attention given to the presence and duration of fever, night sweats, and unexplained weight loss of 10% or more of body weight in the previous 6 months.Biopsy (preferably excisional), with interpretation by a qualified pathologist.For more information, see Hot Flashes and Night Sweats, Pruritus, and Fatigue.ĭiagnostic evaluation of patients with lymphoma may include the following: Treatment of HL should relieve these symptoms within days. Pruritus, especially after bathing or after ingesting alcohol.Weight loss of 10% or more of baseline weight in the previous 6 months.Painless, swollen lymph nodes in the neck, axilla, or inguinal area.These and other signs and symptoms may be caused by HL or by other conditions: Having a first-degree relative with HL.Having a previous infection with the Epstein-Barr virus in the teenage years or early childhood. ![]() Being in early adulthood (aged 20–39 years) (most often) or late adulthood (aged 65 years and older) (less often).Risk factors for HL include the following: Involvement of Waldeyer's ring or tonsillar lymph glands is rarely seen. HL most frequently presents in lymph node groups above the diaphragm and/or in mediastinal lymph nodes. Up to 90% of all newly diagnosed patients with HL can be cured with combination chemotherapy and/or radiation therapy. General Information About Hodgkin Lymphoma (HL)Įstimated new cases and deaths from HL in the United States in 2023:
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